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产品信息
PA5-58777
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2646717
产品详细信息
Immunogen sequence: KNTITLEVHQ AYSTEYETIA ACQLKFHEIL EKSGRIFCTA SLIGTKGDIP NFGTVEYWFR LRVPMDQAIR LYRERAKALG YITSNFKGPE HMQSLSQQAP KTAQLSSTDS TDGNL
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.
靶标信息
The protein encoded by this gene can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 and Meckel syndrome type 5. Two transcript variants encoding different isoforms have been found for this gene.
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生物信息学
蛋白别名: DKFZp686C0668; fantom homolog; Nephrocystin-8; Protein fantom; protein phosphatase 1, regulatory subunit 134; RPGR-interacting protein 1-like protein; RPGRIP1-like; RPGRIP1-like protein
基因别名: CORS3; FTM; JBTS7; KIAA1005; MKS5; NPHP8; PPP1R134; RPGRIP1L
UniProt ID: (Human) Q68CZ1
Entrez Gene ID: (Human) 23322
in utero embryonic development
establishment of planar polarity
kidney development
liver development
establishment or maintenance of cell polarity
determination of left/right symmetry
regulation of smoothened signaling pathway
neural tube patterning
cerebellum development
lateral ventricle development
olfactory bulb development
corpus callosum development
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
cilium assembly
camera-type eye development
nose development
negative regulation of G-protein coupled receptor protein signaling pathway
pericardium development
cochlea development
