Invitrogen

RPL24 Polyclonal Antibody

RPL24 Antibody in Immunocytochemistry (ICC/IF)

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RPL24 Antibody (PA5-30157) in ICC/IF

RPL24 Polyclonal Antibody detects RPL24 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RPL24 stained by RPL24 Polyclonal Antibody (Product # PA5-30157) diluted at 1:200. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin Polyclonal Antibody [GT114] (Product # MA5-31466) diluted at 1:1,000. Blue: Fluoroshield with DAPI .

Product Image Gallery

RPL24 Antibody — Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. HeLa cells were transfected with RPL24 siRNA and reduction of signal was observed in Western Blot using RPL24 Polyclonal Antibody (Product # PA5-30157). {KD}

产品信息

PA5-30157

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

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产品规格

种属反应

Human, Mouse

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein fragment corresponding to a region within amino acids 1 and 157 of Human RPL24

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.86 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2547631

产品详细信息

Recommended positive controls: A549.

Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (88%), Xenopus laevis (93%), Cat (100%), Chicken (97%), Rhesus Monkey (100%), Bovine (100%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from S. cerevisiae; however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Impaired dynamic interaction of axonal endoplasmic reticulum and ribosomes contributes to defective stimulus-response in spinal muscular atrophy.

Translational neurodegeneration

Deng C,Reinhard S,Hennlein L,Eilts J,Sachs S,Doose S,Jablonka S,Sauer M,Moradi M,Sendtner M

PA5-30157 was used in Immunocytochemistry-immunoflourescence to implicate impaired dynamic interplay between the ribosomes and ER in axon terminals of motoneurons as a contributor to the pathophysiology of SMA and possibly also other motoneuron diseases.

Thu Jun 02 00:00:00 UTC 2022

Impaired dynamic interaction of axonal endoplasmic reticulum and ribosomes contributes to defective stimulus-response in spinal muscular atrophy.

Translational neurodegeneration

Deng C,Reinhard S,Hennlein L,Eilts J,Sachs S,Doose S,Jablonka S,Sauer M,Moradi M,Sendtner M

Thu Jun 02 00:00:00 UTC 2022

生物信息学

蛋白别名: 60S ribosomal protein L24; 60S ribosomal protein L30; belly spot and tail; epididymis secretory protein Li 310; Large ribosomal subunit protein eL24; ribosomal protein L30

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基因别名: 0610008L05Rik; Bst; HEL-S-310; L24; RPL24

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UniProt ID: (Human) P83731, (Mouse) Q8BP67

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Entrez Gene ID: (Human) 6152, (Mouse) 68193

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功能

RNA binding structural constituent of ribosome protein binding poly(A) RNA binding cadherin binding involved in cell-cell adhesion ribosomal protein

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