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RPL6 Antibody (PA5-30217) in IHC (P)
RPL6 Polyclonal Antibody detects RPL6 protein at cytoplasm on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded lung carcinoma. RPL6 Polyclonal Antibody (Product # PA5-30217) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-30217
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 7 and 223 of Human RPL6
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547691
产品详细信息
Recommended positive controls: A549, H1299, HCT116, MCF-7.
Predicted reactivity: Mouse (91%), Rat (91%), Xenopus laevis (81%), Pig (94%), Chicken (83%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 60S ribosomal protein L6; DNA-binding protein TAXREB107; Large ribosomal subunit protein eL6; Neoplasm-related protein C140; TAX-responsive enhancer element-binding protein 107; TAXREB107
基因别名: L6; RPL6; SHUJUN-2; TAXREB107; TXREB1
UniProt ID: (Human) Q02878, (Mouse) P47911, (Rat) P21533
Entrez Gene ID: (Human) 6128, (Mouse) 19988, (Rat) 117042
ribosomal large subunit assembly
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
cytoplasmic translation
regulation of transcription, DNA-templated
rRNA processing
translation
translational initiation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
cell-cell adhesion
