Invitrogen

RPP30 Polyclonal Antibody

RPP30 Antibody in Immunocytochemistry (ICC/IF)

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RPP30 Antibody (PA5-58019) in ICC/IF

Immunofluorecent analysis of RPP30 in human cell line U-251 MG using RPP30 Polyclonal Antibody (Product # PA5-58019). Staining shows localization to nucleus, nucleoli and microtubule ends.

RPP30 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RPP30 Antibody in Immunohistochemistry (IHC)

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RPP30 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of RPP30 demonstrates antibody specificity. Immunohistochemical analysis of RPP30 using anti-RPP30 Polyclonal Antibody (Product # PA5-58019), shows significant staining of RPP30 in human testis and shows minimal or weak staining in human pancreas tissues. The relative expression levels of RPP30 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-58019

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human RPP30. Recombinant protein control fragment (Product #RP-97107).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2646765

产品详细信息

Immunogen sequence: NVIISSAAER PLEIRGPYDV ANLGLLFGLS ESDAKAAVST NCRAALLHGE TRKTAFGIIS TVKKPRPSEG DEDCLPASKK AKCEG

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 85%.

靶标信息

RNase P, which consists of a complex of an RNA species (H1 RNA), POP1 (Processing of Precursor 1), POP5 (Processing of Precursor 5), and at least seven Rpps (including Rpp14, Rpp29, Rpp30 and Rpp38), removes the 5' leader sequences from precursor tRNA molecules. The structurally related RNase MRP plays an essential role in the formation of the 5' end of 5.8S rRNA. Both RNase P and RNase MRP are associated with Th/To ribonucleoproteins; Rpp30 and Rpp38 have specifically been implicated as Th autoantigens which contribute to the autoimmune disease systemic sclerosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。