Search Thermo Fisher Scientific
Peptide sequence: RTGSQGQCTQ VRVEFMDDTS RSIIRNVKGP VREGDVLTLL ESEREARRLR
Sequence homology: Cow: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 93%; Zebrafish: 100%
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 40S ribosomal protein S28; Small ribosomal subunit protein eS28
基因别名: DBA15; RPS28; S28
UniProt ID: (Human) P62857
Entrez Gene ID: (Human) 6234