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Immunogen sequence: MDTSRVQPIK LARVTKVLGR TGSQGQCTQV RVEFMDDTSR SIIRNVKGPV REGDVLTLLE SEREARRLR
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 40S ribosomal protein S28; Small ribosomal subunit protein eS28
基因别名: DBA15; RPS28; S28
UniProt ID: (Human) P62857
Entrez Gene ID: (Human) 6234