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RREB1 Antibody (PA5-116933) in WB
Western blot analysis of RREB1 in extracts of various cell lines. Samples were incubated with RREB1 Polyclonal antibody (Product # PA5-116933) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-116933
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 350-480 of human RREB1 (NP_0010036981)
偶联物
形式
Liquid
浓度
1.45 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901563
产品详细信息
Positive Samples: Jurkat, U-251MG, Rat lung
Immunogen sequence: ATPLPGDALD QKGFLALLGL QHTKDVRPAP AEEPLPDDNQ AIQLQTLKCQ LPQDPGCTNL LSLSPFEAAS LGGSLTVLPA TKDSIKHLSL QPFQKGFIIQ PDSSIVVKPI SGESAIELAD IQQILKMAAS A
靶标信息
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA-binding protein; Finger protein in nuclear bodies; hindsight homolog; Raf-responsive zinc finger protein LZ321; Ras-responsive element-binding protein 1; RREB 1; RREB-1; Zep 1; Zep-1; Zep1; zinc finger motif enhancer binding protein 1; Zinc finger motif enhancer-binding protein 1; zinc finger motif-enhancer binding-protein 1
基因别名: FINB; HNT; LZ321; RREB-1; RREB1; Zep-1
UniProt ID: (Human) Q92766
Entrez Gene ID: (Human) 6239, (Rat) 306873
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
Ras protein signal transduction
multicellular organism development
positive regulation of epithelial cell migration
positive regulation of mammary gland epithelial cell proliferation
positive regulation of transcription, DNA-templated
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of wound healing, spreading of epidermal cells
positive regulation of lamellipodium morphogenesis
negative regulation of transcription, DNA-templated
