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RSPO4 is a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hRspo4; R-spondin family, member 4; R-spondin-4; Roof plate-specific spondin-4
基因别名: C20orf182; CRISTIN4; RSPO4
UniProt ID: (Human) Q2I0M5
Entrez Gene ID: (Human) 343637