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In Western blots, 50-100% cross-reactivity with recombinant human (rh) R-Spondin 4 is observed and no cross-reactivity with recombinant mouse (rm) R-Spondin 1, rmR-Spondin 3, or rhR-Spondin 2 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
RSPO4 is a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cristin-4; Cysteine-rich and single thrombospondin domain-containing protein 4; mCristin-4; R-spondin-4; R-spondin-like protein; Roof plate-specific spondin-4
基因别名: A730099F22; A930029K19Rik; Rspo4
UniProt ID: (Mouse) Q8BJ73
Entrez Gene ID: (Mouse) 228770