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RUVBL1 Antibody (PA5-29278) in ICC/IF
Immunofluorescence analysis of RUVBL1 was performed using 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with RUVBL1 Rabbit Polyclonal Antibody (Product # PA5-29278) at 5 µg/mL in 0.1% BSA and incubated overnight at 4 degree and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) ... View More
产品信息
PA5-29278
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 57 and 345 of Human RUVBL1
偶联物
形式
Liquid
浓度
0.32 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546754
产品详细信息
Recommended positive controls: A549, H1299, HCT116.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (97%), Xenopus laevis (97%), Chicken (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; DNA helicase p50; ECP-54; INO80 complex subunit H; NMP 238; Nuclear matrix protein 238; Pontin 52; RuvB (E coli homolog)-like 1; RuvB-like 1; RuvB-like AAA ATPase 1; RuvB-like protein 1; TAP54-alpha; TATA binding protein interacting protein 49 kDa; TIP49a; TIP60-a; TIP60-associated protein 54-alpha
基因别名: 2510009G06Rik; ECP-54; ECP54; INO80H; NMP 238; NMP238; PONTIN; Pontin52; RUVBL1; RVB1; TIH1; TIP49; TIP49A
UniProt ID: (Human) Q9Y265, (Rat) P60123, (Mouse) P60122
Entrez Gene ID: (Human) 8607, (Rat) 65137, (Mouse) 56505
DNA repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
mitotic nuclear division
positive regulation of plasminogen activation
DNA duplex unwinding
regulation of growth
histone H4 acetylation
histone H2A acetylation
cell division
regulation of fibroblast apoptotic process
cellular response to DNA damage stimulus
cell cycle
chromatin modification
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
box C/D snoRNP assembly
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
spermatogenesis
CENP-A containing nucleosome assembly
cell-cell adhesion
beta-catenin-TCF complex assembly
positive regulation of telomerase RNA localization to Cajal body
