Abnova

RYK Polyclonal Antibody, MaxPab™

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RYK Antibody (H00006259-B01P) in WB

Western Blot analysis of RYK expression in transfected 293T cell line by RYK MaxPab polyclonal antibody. Lane 1: RYK transfected lysate(67.1 KDa). Lane 2: Non-transfected lysate. .

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产品信息

H00006259-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

RYK (AAI53091.1, 1 a.a. approximately 610 a.a) full-length human protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MRGAARLGRP GRSCLPGARG LRAPPPPPLL LLLALLPLLP APGAAAAPAP RPPELQSASA GPSVSLYLSE DEVRRLIGLD AELYYVRNDL ISHYALSFSL LVPSETNFLH FTWHAKSKVE YKLGFQVDNV LAMDMPQVNI SVQGEVPRTL SVFRVELSCT GKVDSEVMIL MQLNLTVNSS KNFTVLNFKR RKMCYKKLEE VKTSALDKNT SRTIYDPVHA APTTSTRVFY ISVGVCCAVI FLVAIILAVL HLHSMKRIEL DDSISASSSS QGLSQPSTQT TQYLRADTPN NATPITSSLG YPTLRIEKND LRSVTLLEAK GKVKDIAISR ERITLKDVLQ EGTFGRIFHG ILIDEKDPNK EKQAFVKTVK DQASEIQVTM MLTESCKLRG LHHRNLLPIT HVCIEEGEKP MVILPYMNWG NLKLFLRQCK LVEANNPQAI SQQDLVHMAI QIACGMSYLA RREVIHKDLA ARNCVIDDTL QVKITDNALS RDLFPMDYHC LGDNENRPVR WMALESLVNN EFSSASDVWA FGVTLWELMT LGQTPYVDID PFEMAAYLKD GYRIAQPINC PDELFAVMAC CWALDPEERP KFQQLVQCLT EFHAALGAYV

靶标信息

RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.

仅用于科研。不用于诊断过程。未经明确授权不得转售。