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Raptor Antibody (PA5-85717) in IHC (P)
Raptor Polyclonal Antibody detects Raptor protein at cytoplasm in rat intestine by immunohistochemical analysis. Sample: Paraffin-embedded rat intestine. Raptor Polyclonal Antibody (Product # PA5-85717) diluted at 1:1500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-85717
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Raptor.
偶联物
形式
Liquid
浓度
0.56 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792856
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Bovine (100%).
Positive Control: 293T, A431, HeLa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Raptor; regulatory associated protein of MTOR, complex 1; Regulatory-associated protein of mTOR
基因别名: KIAA1303; KOG1; Mip1; RAPTOR; RGD1311784; RPTOR
UniProt ID: (Human) Q8N122
Entrez Gene ID: (Human) 57521, (Rat) 287871
RNA polymerase III type 1 promoter DNA binding
RNA polymerase III type 2 promoter DNA binding
RNA polymerase III type 3 promoter DNA binding
TFIIIC-class transcription factor binding
protein binding
protein kinase binding
protein kinase activator activity
protein binding, bridging
protein complex binding
14-3-3 protein binding
positive regulation of endothelial cell proliferation
regulation of cell size
cell growth
cellular response to nutrient levels
TOR signaling
positive regulation of TOR signaling
regulation of phosphorylation
positive regulation of transcription from RNA polymerase III promoter
cellular response to amino acid stimulus
positive regulation of protein serine/threonine kinase activity
cell cycle arrest
macroautophagy
activation of protein kinase activity
regulation of cellular response to heat
