NeoBiotechnologies

Ras-related C3 botulinum toxin substrate 1 Monoclonal Antibody (CPTC-RAC1-1)

查看其他8个RAC1抗体

抗体检测数据 (4)

Ras-related C3 botulinum toxin substrate 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Ras-related C3 botulinum toxin substrate 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Ras-related C3 botulinum toxin substrate 1 Antibody (5879-MSM1-P1ABX) in IHC (P)

Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human lung using Ras-related C3 botulinum toxin substrate 1 Monoclonal Antibody (Product # 5879-MSM1-P1ABX).

Ras-related C3 botulinum toxin substrate 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Ras-related C3 botulinum toxin substrate 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Ras-related C3 botulinum toxin substrate 1 Antibody in Peptide array (ARRAY)

Ras-related C3 botulinum toxin substrate 1 Antibody in SDS-PAGE (SDS-PAGE)

Product Image Gallery

Ras-related C3 botulinum toxin substrate 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human lung using Ras-related C3 botulinum toxin substrate 1 Monoclonal Antibody (Product # 5879-MSM1-P1ABX).

Ras-related C3 botulinum toxin substrate 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human lung using Ras-related C3 botulinum toxin substrate 1 Monoclonal Antibody (Product # 5879-MSM1-P1ABX).

Ras-related C3 botulinum toxin substrate 1 Antibody in Peptide array (ARRAY) — Analysis of Protein Array containing more than 19,000 full-length human proteins Ras-related C3 botulinum toxin substrate 1 Monoclonal Antibody (Product # 5879-MSM1-P1ABX). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Ras-related C3 botulinum toxin substrate 1 Antibody in SDS-PAGE (SDS-PAGE) — SDS-PAGE Analyis Purified Ras-related C3 botulinum toxin substrate 1 Monoclonal Antibody (Product # 5879-MSM1-P1ABX). Confirmation of Purity and Integrity of Antibody.

产品信息

5879-MSM1-P1ABX

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

-

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

-

免疫细胞化学 (ICC/IF)

1-2 µg/mL

-

肽阵列 (Array)

Assay-dependent

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

CPTC-RAC1-1

抗原

Recombinant human full-length RAC1protein

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C or -80°C if preferred

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Antibody is tested in direct ELISA.

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

靶标信息

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Cell migration-inducing gene 5 protein; MGC111543; p21-Rac1; Ras-like protein TC25; Ras-related C3 botulinum toxin substrate 1

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基因别名: MIG5; p21-Rac1; Rac-1; RAC1; TC-25; TC25

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UniProt ID: (Human) P63000

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Entrez Gene ID: (Human) 5879

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GTPase activity protein binding GTP binding Rab GTPase binding enzyme binding protein kinase binding GTP-dependent protein binding thioesterase binding histone deacetylase binding Rho GDP-dissociation inhibitor binding small GTPase

positive regulation of protein phosphorylation auditory receptor cell morphogenesis mast cell chemotaxis epithelial cell morphogenesis movement of cell or subcellular component inflammatory response hyperosmotic response cell adhesion cell-matrix adhesion G-protein coupled receptor signaling pathway small GTPase mediated signal transduction axon guidance blood coagulation cell proliferation regulation of cell size response to wounding anatomical structure morphogenesis regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly regulation of fibroblast migration positive regulation of cell-substrate adhesion regulation of neuron maturation cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration cerebral cortex GABAergic interneuron development lamellipodium assembly actin cytoskeleton organization actin filament polymerization platelet activation regulation of cell migration positive regulation of actin filament polymerization T cell costimulation ruffle organization negative regulation of interleukin-23 production substrate adhesion-dependent cell spreading positive regulation of Rho protein signal transduction intracellular signal transduction Fc-epsilon receptor signaling pathway Fc-gamma receptor signaling pathway involved in phagocytosis positive regulation of apoptotic process positive regulation of phosphatidylinositol 3-kinase activity engulfment of apoptotic cell cell-cell junction organization bone resorption positive regulation of DNA replication vascular endothelial growth factor receptor signaling pathway ephrin receptor signaling pathway negative regulation of receptor-mediated endocytosis anatomical structure arrangement dendrite morphogenesis cell motility homeostasis of number of cells within a tissue regulation of defense response to virus by virus regulation of small GTPase mediated signal transduction positive regulation of stress fiber assembly localization within membrane positive regulation of focal adhesion assembly synaptic transmission, GABAergic Wnt signaling pathway, planar cell polarity pathway regulation of respiratory burst cellular response to mechanical stimulus semaphorin-plexin signaling pathway dopaminergic neuron differentiation protein localization to plasma membrane positive regulation of neutrophil chemotaxis cochlea morphogenesis ruffle assembly positive regulation of substrate adhesion-dependent cell spreading