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Rhodopsin Antibody (OSR00220W-100UL) in IHC (P)
IHC-P on paraffin sections of mouse eye. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 mL 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions; DAB chromogen: Candela DAB chromo... View More
产品信息
OSR00220W-100UL
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from human Rhodopsin conjugated to blue carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in mouse and rat.
Specificity of this antibody: Rhodopsin.
靶标信息
Visual pigments such as rhodopsin and porphyropsin are light-absorbing molecules that mediate vision. Rhodopsin consists of an apoprotein, opsin, covalently linked to 11-cis-retinal. This receptor is coupled to the activation of phospholipase C. Porphyropsin consists of opsin covalently linked to 11-cis 3,4-didehydroretinal.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: L opsin; Long Wavelength Sensitive opsin; LWS opsin; MGC138309; MGC138311; OPN 2; opsin 2; opsin 2, rod pigment; Opsin-2; Red Opsin; Rhodopsin; Rhodopsin (retinitis pigmentosa 4, autosomal dominant); Rod Opsin; RP 4
基因别名: CSNBAD1; Noerg1; OPN2; Ops; RHO; RP4
UniProt ID: (Human) P08100, (Rat) P51489, (Mouse) P15409
Entrez Gene ID: (Human) 6010, (Rat) 24717, (Mouse) 212541
retinoid metabolic process
protein phosphorylation
G-protein coupled receptor signaling pathway
visual perception
phototransduction, visible light
red, far-red light phototransduction
absorption of visible light
rhodopsin mediated signaling pathway
protein-chromophore linkage
regulation of rhodopsin mediated signaling pathway
photoreceptor cell maintenance
retina development in camera-type eye
phototransduction
response to light stimulus
detection of light stimulus
sensory perception of light stimulus
cellular response to light stimulus
signal transduction
response to stimulus
