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Invitrogen
Rhodopsin Recombinant Rabbit Monoclonal Antibody (JA10-91)
Product Details
MA5-32659
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JA10-91
Immunogen
Synthetic peptide within Human Rhodopsin aa 299-348
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2809936
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Visual pigments such as rhodopsin and porphyropsin are light-absorbing molecules that mediate vision. Rhodopsin consists of an apoprotein, opsin, covalently linked to 11-cis-retinal. This receptor is coupled to the activation of phospholipase C. Porphyropsin consists of opsin covalently linked to 11-cis 3,4-didehydroretinal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC138309; MGC138311; OPN 2; opsin 2, rod pigment; Opsin-2; Rhodopsin; Rhodopsin (retinitis pigmentosa 4, autosomal dominant); RP 4
Gene Aliases: CSNBAD1; OPN2; RHO; RP4
UniProt ID: (Human) P08100, (Rat) P51489
Entrez Gene ID: (Human) 6010, (Rat) 24717
retinoid metabolic process
protein phosphorylation
G-protein coupled receptor signaling pathway
visual perception
phototransduction, visible light
red, far-red light phototransduction
absorption of visible light
rhodopsin mediated signaling pathway
protein-chromophore linkage
regulation of rhodopsin mediated signaling pathway
photoreceptor cell maintenance
retina development in camera-type eye
phototransduction
response to light stimulus
detection of light stimulus
sensory perception of light stimulus
cellular response to light stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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