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产品信息
PA5-109277
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within Human RYR1 aa 1,354-1,403
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2854688
产品详细信息
Positive Control: Human fetal skeletal muscle tissue, mouse cerebellum tissue, SiHa.
靶标信息
Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscled cells. Ryanodine receptor, ~500 kDa, can be isolated from a variety of cell types such as lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscles, cardiac muscle and brain tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium release channel; central core disease of muscle; protein phosphatase 1, regulatory subunit 137; Ryanodine receptor; Ryanodine receptor 1; ryanodine receptor 1 (skeletal); ryanodine receptor 1, skeletal muscle; ryanodine receptor 1-like, skeletal muscle; RYR-1; sarcoplasmic reticulum calcium release channel; Skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; Skeletal muscle-type ryanodine receptor; Type 1 ryanodine receptor; type 1-like ryanodine receptor
基因别名: AI528790; CCO; MHS; MHS1; PPP1R137; RYDR; RYR; RYR-1; RYR1; Ryr1l; SKRR
UniProt ID: (Human) P21817, (Mouse) E9PZQ0
Entrez Gene ID: (Human) 6261, (Mouse) 20190, (Rat) 114207
protease binding
ryanodine-sensitive calcium-release channel activity
voltage-gated calcium channel activity
calcium channel activity
calcium ion binding
protein binding
calmodulin binding
calcium-release channel activity
ion channel activity
enzyme binding
ligand-gated ion channel
scaffold/adaptor protein
response to hypoxia
outflow tract morphogenesis
calcium ion transport
muscle contraction
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
response to caffeine
ion transmembrane transport
skin development
ossification involved in bone maturation
skeletal muscle fiber development
release of sequestered calcium ion into cytosol
regulation of cytosolic calcium ion concentration
cellular response to caffeine
regulation of cardiac conduction
transport
ion transport
cellular calcium ion homeostasis
regulation of muscle contraction
multicellular organism development
regulation of ion transmembrane transport
transmembrane transport
sarcoplasmic reticulum calcium ion transport
calcium ion transmembrane transport
