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S100A8 Antibody (PA5-47439) in ICC/IF
Immunocytochemistry analysis of S100A8 in immersion fixed NMuMG mouse mammary gland epithelial cell line. Samples were incubated in S100A8 polyclonal antibody (Product # PA5-47439) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue).
产品信息
PA5-47439
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant mouse S100A8 Pro2-Glu89
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609087
产品详细信息
In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant mouse (rm) S100A9, rmS100A10, and recombinant human S100B is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calgranulin-A; Chemotactic cytokine CP-10; chemotactic S100 protein; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; p8; Pro-inflammatory S100 cytokine; Protein S100-A8; S100 A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A)
基因别名: 60B8Ag; AI323541; B8Ag; Caga; CFAg; CP-10; MRP8; p8; S100a8
UniProt ID: (Rat) P50115, (Mouse) P27005
Entrez Gene ID: (Rat) 116547, (Mouse) 20201
leukocyte migration involved in inflammatory response
acute inflammatory response
chronic inflammatory response
positive regulation of peptide secretion
autophagy
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
response to zinc ion
neutrophil chemotaxis
response to lipopolysaccharide
wound healing
innate immune response
response to ethanol
positive regulation of inflammatory response
neutrophil aggregation
positive regulation of intrinsic apoptotic signaling pathway
immune system process
apoptotic process
chemotaxis
peptidyl-cysteine S-nitrosylation
regulation of inflammatory response
