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SAB Antibody (PA5-100332) in ICC/IF
Immunofluorescent analysis of SAB in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and SAB polyclonal antibody (Product # PA5-100332) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-100332
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SH3BP5(Accession O60239), corresponding to amino acid residues Q33-K83.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2849846
产品详细信息
Antibody detects endogenous levels of total SH3BP5.
靶标信息
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SH3 binding protein; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3-domain binding protein 5 (BTK-associated); SH3BP-5; Vascular endothelial cell-specific protein 18
基因别名: AI606498; SAB; SH3BP-5; SH3BP5; Vesp18
UniProt ID: (Human) O60239, (Rat) Q91Y80, (Mouse) Q9Z131
Entrez Gene ID: (Human) 9467, (Rat) 117186, (Mouse) 24056
