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SAE1 Antibody (PA5-22297) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of SAE1 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: SAE1 Polyclonal Antibody (Product # PA5-22297) diluted at 1:500. Red: phalloidin, a cytoskeleton marker. Scale bar = 10 µm.
产品信息
PA5-22297
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 3 and 247 of SAE1 (Uniprot ID#Q9UBE0)
偶联物
形式
Liquid
浓度
0.72 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11153590
产品详细信息
Recommended positive controls: A431, H1299, mouse brain, Rat2.
Predicted reactivity: Mouse (94%), Rat (93%), Chimpanzee (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2. form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: activator of SUMO1; FLJ3091; sentrin/SUMO-activating protein AOS1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; ubiquitin-like (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme E1A; ubiquitin-like 1 (sentrin) activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; ubiquitin-like protein SUMO-1 activating enzyme
基因别名: 2400010M20Rik; 2610044L12Rik; AL033372; AOS1; AW743391; D7Ertd177e; HSPC140; SAE1; SUA1; Ubl1a1; UBLE1A
UniProt ID: (Human) Q9UBE0, (Mouse) Q9R1T2, (Rat) Q6AXQ0
Entrez Gene ID: (Human) 10055, (Mouse) 56459, (Rat) 308384
