Invitrogen

SAMHD1 Monoclonal Antibody (OTI1F6)

SAMHD1 Antibody in Immunocytochemistry (ICC/IF)

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SAMHD1 Antibody (MA5-25298) in ICC/IF

Immunofluorescence analysis of SAMHD1 was performed using 70% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with SAMHD1 Monoclonal Antibody (OTI1F6) (Product # MA5-25298) at 1:100 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Produc... View More

SAMHD1 Antibody in Immunohistochemistry (IHC)

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产品信息

MA5-25298

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

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免疫组化 (IHC)

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免疫细胞化学 (ICC/IF)

1:100

流式细胞分析 (Flow)

1:100

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产品规格

种属反应

Human, Mouse, Non-human primate, Rat

已发表种属

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

OTI1F6

抗原

Full length human recombinant protein of SAMHD1 produced in HEK293T cell

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.72 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 1% BSA, 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2725289

靶标信息

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.

International journal of cancer

Roider T,Wang X,Hüttl K,Müller-Tidow C,Klapper W,Rosenwald A,Stewart JP,de Castro DG,Dreger P,Hermine O,Kluin-Nelemans HC,Grabe N,Dreyling M,Pott C,Ott G,Hoster E,Dietrich S

MA5-25298 was used in Western Blot, Flow Cytometry to evaluate the SAMHD1 protein as potential biomarker for the response to high-dose cytarabine in mantle cell lymphoma patients.

Fri Jan 01 00:00:00 UTC 2021

The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.

International journal of cancer

Roider T,Wang X,Hüttl K,Müller-Tidow C,Klapper W,Rosenwald A,Stewart JP,de Castro DG,Dreger P,Hermine O,Kluin-Nelemans HC,Grabe N,Dreyling M,Pott C,Ott G,Hoster E,Dietrich S

MA5-25298 was used in Western Blot, Flow Cytometry to evaluate the SAMHD1 protein as potential biomarker for the response to high-dose cytarabine in mantle cell lymphoma patients.

Fri Jan 01 00:00:00 UTC 2021

The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.

International journal of cancer

Roider T,Wang X,Hüttl K,Müller-Tidow C,Klapper W,Rosenwald A,Stewart JP,de Castro DG,Dreger P,Hermine O,Kluin-Nelemans HC,Grabe N,Dreyling M,Pott C,Ott G,Hoster E,Dietrich S

MA5-25298 was used in Western Blot, Flow Cytometry to evaluate the SAMHD1 protein as potential biomarker for the response to high-dose cytarabine in mantle cell lymphoma patients.

Fri Jan 01 00:00:00 UTC 2021

The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.

International journal of cancer

Roider T,Wang X,Hüttl K,Müller-Tidow C,Klapper W,Rosenwald A,Stewart JP,de Castro DG,Dreger P,Hermine O,Kluin-Nelemans HC,Grabe N,Dreyling M,Pott C,Ott G,Hoster E,Dietrich S

MA5-25298 was used in Western Blot, Flow Cytometry to evaluate the SAMHD1 protein as potential biomarker for the response to high-dose cytarabine in mantle cell lymphoma patients.

Fri Jan 01 00:00:00 UTC 2021

生物信息学

蛋白别名: DCIP; Dendritic cell-derived IFNG-induced protein; Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; hSAMHD1; IFN-gamma induced; Interferon-gamma-inducible protein Mg11; Monocyte protein 5; MOP-5; mSAMHD1; RP1-132F21.1; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1

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基因别名: CHBL2; DCIP; E330031J07Rik; HDDC1; Mg11; Mg21; MOP-5; MOP5; SAMHD1; SBBI88

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UniProt ID: (Human) Q9Y3Z3, (Mouse) Q60710

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Entrez Gene ID: (Human) 25939, (Rat) 311580, (Mouse) 56045

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功能