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产品信息
PA5-111361
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2856771
产品详细信息
Immunogen sequence: QIYNIDPARF KDLNLAGTAE VGLAGYFMDH TVAFRDLPVR MVCSSTCYRA ETNTGQEPRG LYRVHHFTKV EMFGVTGPGL
靶标信息
This gene encodes the mitochondrial seryl-tRNA synthetase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.
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生物信息学
蛋白别名: EC 6.1.1.11; mitochondrial seryl-tRNA synthetase; serine tRNA ligase 2, mitochondrial; Serine--tRNA ligase, mitochondrial; serine-tRNA ligase; serine-tRNA ligase, mitochondrial; SerRS; SerRSmt; Seryl-tRNA synthetase; seryl-tRNA synthetase, mitochondrial; Seryl-tRNA(Ser/Sec) synthetase
基因别名: mtSerRS; SARS; SARS2; SARSM; SerRS; SerRSmt; SERS; SYS
UniProt ID: (Human) Q9NP81
Entrez Gene ID: (Human) 54938
