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Immunogen sequence: EASMAKYYAS EIAGQTTSKC IEWMGGVGYT KDYPVEKYFR DAKIGTIYEG ASNIQLNTIA KHIDAE
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 92%.
Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7- kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-MEBCAD; 2-methyl branched chain acyl-CoA dehydrogenase; 2-methylbutyryl-CoA dehydrogenase; 2-methylbutyryl-coenzyme A dehydrogenase; acyl-CoA dehydrogenase short/branched chain; acyl-Coenzyme A dehydrogenase, short/branched chain; SBCAD; Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
Gene Aliases: 2-MEBCAD; ACAD7; ACADSB; SBCAD
UniProt ID: (Human) P45954
Entrez Gene ID: (Human) 36
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