Invitrogen

SDF1 Polyclonal Antibody

SDF1 Antibody in Immunocytochemistry (ICC/IF)

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SDF1 Antibody (PA5-114344) in ICC/IF

Immunocytochemical analysis of SDF1 in LOVO cells using a SDF1 polyclonal antibody (Product #PA5-114344). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with the primary antibody for 1 hour at room temperature, washed with PBS. Alexa Fluor®488 Goat anti-Rabbit IgG was used as the secondary antibody at 1:100 dilution. The nuclear counter stain is DAPI.

SDF1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SDF1 Antibody in Immunohistochemistry (IHC)

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产品信息

PA5-114344

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500

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免疫组化 (IHC)

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:600

免疫细胞化学 (ICC/IF)

1:100-1:500

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流式细胞分析 (Flow)

1:50-1:100

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein within human SDF1 alpha aa 1-93

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 0.2% BSA, 50% glycerol

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2890495

靶标信息

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The SDF1-CXCR4 Axis Is Involved in the Hyperbaric Oxygen Therapy-Mediated Neuronal Cells Migration in Transient Brain Ischemic Rats.

International journal of molecular sciences

Wang RY,Yang YR,Chang HC

PA5-114344 was used in Western Blot to explore the effects of HBOT on the neurogenesis and the expressions of cell migration factors, including the stromal cell-derived factor 1 (SDF1) and its target receptor, the CXC chemokine receptor 4 (CXCR4).

Fri Feb 04 00:00:00 UTC 2022

The SDF1-CXCR4 Axis Is Involved in the Hyperbaric Oxygen Therapy-Mediated Neuronal Cells Migration in Transient Brain Ischemic Rats.

International journal of molecular sciences

Wang RY,Yang YR,Chang HC

Fri Feb 04 00:00:00 UTC 2022

The SDF1-CXCR4 Axis Is Involved in the Hyperbaric Oxygen Therapy-Mediated Neuronal Cells Migration in Transient Brain Ischemic Rats.

International journal of molecular sciences

Wang RY,Yang YR,Chang HC

Fri Feb 04 00:00:00 UTC 2022

Use of gliptins reduces levels of SDF-1/CXCL12 in bullous pemphigoid and type 2 diabetes, but does not increase autoantibodies against BP180 in diabetic patients.

Frontiers in immunology

Nätynki A,Leisti P,Tuusa J,Varpuluoma O,Huilaja L,Izumi K,Herukka SK,Ukkola O,Junttila J,Kokkonen N,Tasanen K

PA5-114344 was used in Immunohistochemistry to explore the mechanism behind gliptin-associated bullous pemphigoid.

Mon Aug 15 00:00:00 UTC 2022

Use of gliptins reduces levels of SDF-1/CXCL12 in bullous pemphigoid and type 2 diabetes, but does not increase autoantibodies against BP180 in diabetic patients.

Frontiers in immunology

Nätynki A,Leisti P,Tuusa J,Varpuluoma O,Huilaja L,Izumi K,Herukka SK,Ukkola O,Junttila J,Kokkonen N,Tasanen K

PA5-114344 was used in Immunohistochemistry to explore the mechanism behind gliptin-associated bullous pemphigoid.

Mon Aug 15 00:00:00 UTC 2022

Single Cell Analysis of Cultivated Fibroblasts from Chronic Pancreatitis and Pancreatic Cancer Patients.

Cells

Sunami Y,Chen Y,Trojanowicz B,Sommerer M,Hämmerle M,Eils R,Kleeff J

PA5-114344 was used in Immunohistochemistry and Immunocytochemistry to identify a myCAFs-like subtype in all cases.

Fri Aug 19 00:00:00 UTC 2022

Single Cell Analysis of Cultivated Fibroblasts from Chronic Pancreatitis and Pancreatic Cancer Patients.

Cells

Sunami Y,Chen Y,Trojanowicz B,Sommerer M,Hämmerle M,Eils R,Kleeff J

PA5-114344 was used in Immunohistochemistry and Immunocytochemistry to identify a myCAFs-like subtype in all cases.

Fri Aug 19 00:00:00 UTC 2022

生物信息学

蛋白别名: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; AI174028; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 12; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; CXCL; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; Pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SDF-1; SDF-1 gamma; SDF-1a; SDF-1b; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; Thymic lymphoma cell-stimulating factor; TLSF; TLSF-a; TLSF-b; Tlsfa; Tlsfb; TPAR1

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基因别名: CXCL12; IRH; PBSF; SCYB12; SDF1; SDF1A; SDF1B; TLSF; TPAR1

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UniProt ID: (Human) Q5IT36, (Mouse) P40224

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Entrez Gene ID: (Human) 6387, (Rat) 24772, (Mouse) 20315

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功能

receptor binding chemokine activity growth factor activity chemoattractant activity chemokine receptor binding CXCR chemokine receptor binding cytokine activity

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