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This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Flavoprotein subunit of complex II; Fp; Malate dehydrogenase [quinone] flavoprotein subunit; Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
基因别名: 1500032O14Rik; 2310034D06Rik; 4921513A11; C81073; FP; SDH2; Sdha; SDHF
UniProt ID: (Rat) Q920L2, (Mouse) Q8K2B3
Entrez Gene ID: (Rat) 157074, (Mouse) 66945