Invitrogen

SDR16C5 Polyclonal Antibody

SDR16C5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SDR16C5 Antibody (PA5-31421) in IHC (P)

Immunohistochemical analysis of paraffin-embedded MDA-MB468 xenograft, using SDR16C5 (Product # PA5-31421) antibody at 1:100 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.

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产品信息

PA5-31421

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:10,000

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 40 and 309 of Human SDR16C5

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 1% BSA, 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2548895

产品详细信息

Recommended positive controls: IMR32.

Predicted reactivity: Mouse (83%), Rat (86%), Pig (82%), Sheep (83%), Rhesus Monkey (93%), Bovine (82%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

SDR16C5 promotes proliferation and migration and inhibits apoptosis in pancreatic cancer.

Open life sciences

Hong K,Yang Q,Yin H,Zhang J,Yu B

PA5-31421 was used in Western Blotting to provide evidence that SDR16C5 is overexpressed in PAAD patients and promotes its proliferation, migration, invasion, and apoptosis-inhibition of PAAD cells.

Sat Jul 01 00:00:00 UTC 2023

SDR16C5 promotes proliferation and migration and inhibits apoptosis in pancreatic cancer.

Open life sciences

Hong K,Yang Q,Yin H,Zhang J,Yu B

PA5-31421 was used in Western Blotting to provide evidence that SDR16C5 is overexpressed in PAAD patients and promotes its proliferation, migration, invasion, and apoptosis-inhibition of PAAD cells.

Sat Jul 01 00:00:00 UTC 2023

Identification of Critical Genes and Proteins for Stent Restenosis Induced by Esophageal Benign Hyperplasia in Esophageal Cancer.

Frontiers in genetics

Weng L,Shen S,Wu S,Yin X,Liu B,Shang M,Zou X,Mao A

PA5-31421 was used in Western Blotting to explore potential genes and proteins associated with esophagus benign hyperplasia induced by esophageal stents.

Fri Nov 10 00:00:00 UTC 2023

Identification of Critical Genes and Proteins for Stent Restenosis Induced by Esophageal Benign Hyperplasia in Esophageal Cancer.

Frontiers in genetics

Weng L,Shen S,Wu S,Yin X,Liu B,Shang M,Zou X,Mao A

PA5-31421 was used in Western Blotting to explore potential genes and proteins associated with esophagus benign hyperplasia induced by esophageal stents.

Fri Nov 10 00:00:00 UTC 2023

生物信息学

蛋白别名: EPHD-2; epidermal retinal dehydrogenase 2; Epidermal retinol dehydrogenase 2; retinal short chain dehydrogenase reductase; Retinal short-chain dehydrogenase reductase 2; retSDR2; Short-chain dehydrogenase/reductase family 16C member 5

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基因别名: EPHD-2; RDH#2; RDH-E2; RDHE2; retSDR2; SDR16C5

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UniProt ID: (Human) Q8N3Y7

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Entrez Gene ID: (Human) 195814

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功能

retinol dehydrogenase activity

参与通路

retinol metabolic process retinal metabolic process keratinocyte proliferation detection of light stimulus involved in visual perception oxidation-reduction process