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Immunogen sequence: HLELKESLSR MGSDLKQGFI SSLKSAWQTL NEFARAHTSS TQLQEELEKV ANQIKEEEEK QVVEAEKVVE SPDFSKDEDY LGKVGML
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 98%.
SEC23IP is involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: p125; SEC23-interacting protein
基因别名: D7Ertd373e; MSTP053; P125; P125A; SEC23IP
UniProt ID: (Human) Q9Y6Y8
Entrez Gene ID: (Human) 11196, (Mouse) 207352, (Rat) 309010