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Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein transport protein Sec24B; SEC24 related gene family, member B; SEC24-related protein B; secretory protein 24
基因别名: SEC24; SEC24B
UniProt ID: (Human) O95487
Entrez Gene ID: (Human) 10427