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Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: protein transport protein Sec24B; SEC24 family, member B; SEC24 related gene family, member B
基因别名: AI605202; SEC24
Entrez Gene ID: (Rat) 295461, (Mouse) 99683