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Keep as concentrated solution.
Predicted reactivity: Dog (100%), Pig (100%).
Positive Control: 293T, A431, HeLa, HepG2, mouse liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. Sec61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. Sec61 alpha is a polytopic protein that has ten membrane-spanning loops. Sec61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: protein translocation complex beta; protein transport protein SEC61 beta subunit; Protein transport protein Sec61 subunit beta; sec61 beta; Sec61 beta subunit; Sec61 complex, beta subunit
基因别名: 1190006C12Rik; AI326121; AW122942; SEC61B
UniProt ID: (Human) P60468, (Mouse) Q9CQS8
Entrez Gene ID: (Human) 10952, (Mouse) 66212