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产品信息
MA5-30850
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
001
抗原
Recombinant Human Semaphorin 6A/SEMA6A protein (Met1-Thr649)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2786527
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human Semaphorin 6A/SEMA6A.
靶标信息
SEMA6A can act as repulsive axon guidance cues. It may play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; Sema VIA; SEMA6A-1; semaphorin 6A-1; Semaphorin VIA; Semaphorin-6A; Semaphorin-6A-1
基因别名: HT018; KIAA1368; SEMA; SEMA6A; SEMA6A1; SEMAQ; VIA
UniProt ID: (Human) Q9H2E6
Entrez Gene ID: (Human) 57556
neural crest cell migration
apoptotic process
cytoskeleton organization
cell surface receptor signaling pathway
nervous system development
axon guidance
organ morphogenesis
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway
positive regulation of neuron migration
