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产品信息
PA1-41260
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acids 500-550 of human SENP2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2254435
产品详细信息
Suggested positive control: HeLa or NIH-3T3 whole cell lysate.
靶标信息
SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Axam2; CT; Sentrin-specific protease 2; Sentrin/SUMO-specific protease SENP2; SMT3-specific isopeptidase 2; Smt3ip2; SUMO-1 protease 1; SUMO-1 protease-1; SUMO-1/Smt3-specific isopeptidase 2; SUMO/sentrin specific protease 2; SUMO1/sentrin/SMT3 specific protease 2; SuPr-1
基因别名: 2310007L05Rik; 4930538C18Rik; AI646780; AW554757; AXAM2; KIAA1331; mKIAA1331; SENP2; SMT3IP2; SuPr-1; Supr1
UniProt ID: (Human) Q9HC62, (Mouse) Q91ZX6
Entrez Gene ID: (Human) 59343, (Mouse) 75826
positive regulation of protein phosphorylation
heart development
dorsal/ventral axis specification
protein transport
Wnt signaling pathway
protein sumoylation
protein desumoylation
regulation of Wnt signaling pathway
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
protein destabilization
negative regulation of protein binding
regulation of DNA endoreduplication
negative regulation of chromatin binding
negative regulation of DNA damage response, signal transduction by p53 class mediator
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mRNA transport
trophoblast giant cell differentiation
labyrinthine layer development
spongiotrophoblast layer development
regulation of G1/S transition of mitotic cell cycle
transcription, DNA-templated
regulation of transcription, DNA-templated
proteolysis
transport
regulation of protein metabolic process
negative regulation of signal transduction by p53 class mediator
