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Antibody detects endogenous levels of total SENP3.
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZP586K0919; DKFZp762A152; Sentrin-specific protease 3; sentrin/SUMO-specific protease 3; Sentrin/SUMO-specific protease SENP3; Smt3-specific isopeptidase 1; Smt3ip1; SUMO-1-specific protease 3; SUMO/sentrin specific peptidase 3; SUMO/sentrin specific protease 3
基因别名: AA408656; SENP3; Smt3ip; SMT3IP1; SSP3; SUSP3; Ulp1
UniProt ID: (Human) Q9H4L4, (Mouse) Q9EP97
Entrez Gene ID: (Human) 26168, (Rat) 303245, (Mouse) 80886