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产品信息
H00205564-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
3C2
抗原
SENP5 (NP_689912, 2 a.a. approximately 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: KKQRKILWRK GIHLAFSEKW NTGFGGFKKF YFHQHLCILK AKLGRPVTWN RQLRHFQGRK KALQIQKTWI KDEHLCAKTK FNVATQNVST LSSKVKRKDA KHFISSSK
靶标信息
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the "GG" region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp564O1016; FLJ42398; MGC27076; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5; SUMO1/sentrin specific protease 5
基因别名: FKSG45; SENP5
UniProt ID: (Human) Q96HI0
Entrez Gene ID: (Human) 205564
