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产品信息
PA5-75186
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 1040-1089 of Human SENP6.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2718914
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Ubiquitin-like molecules, such as SUMO1, are structurally related to ubiquitin. and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1. to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins. SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2810017C20Rik; FLJ11355; FLJ11887; KIAA0389; RP1-134M13.1; Sentrin-specific protease 6; Sentrin/SUMO-specific protease SENP6; SUMO-1-specific protease 1; SUMO/sentrin specific peptidase 6; SUMO/sentrin specific protease 6; SUMO1/sentrin specific protease 6; Sumo1/sentrin/SMT3 specific peptidase 6
基因别名: FKSG6; KIAA0797; SENP6; SSP1; SUSP1
UniProt ID: (Human) Q9GZR1
Entrez Gene ID: (Human) 26054, (Rat) 300860
