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SERC1 Antibody (PA5-99216) in ICC/IF
Immunocytochemistry analysis of SERC1 in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SERC1 polyclonal antibody (Product # PA5-99216) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-99216
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SERC1, corresponding to a region within C-terminal amino acids.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2818149
产品详细信息
Antibody detects endogenous levels of total SERC1.
靶标信息
SERINC1, also named as KIAA1253, TDE1L and TDE2, belongs to the TDE1 family. SERINC1 enhances the incorporation of serine into phosphatidylserine and sphingolipids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: axotomy induced glycoprotein 2; Axotomy-induced glyco/Golgi protein 2; Membrane protein TMS-2; Serine incorporator 1; tumor differentially expressed 1, like; tumor differentially expressed 2; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2
基因别名: 1500011D18Rik; AI315070; AIGP-2; Aigp2; KIAA1253; LRRGT00191; mKIAA1253; SERINC1; TDE1L; TDE2; TMS-2; TMS2; UNQ396/PRO732
UniProt ID: (Human) Q9NRX5, (Mouse) Q9QZI8, (Rat) Q7TNK0
Entrez Gene ID: (Human) 57515, (Mouse) 56442, (Rat) 294421
phosphatidylserine metabolic process
sphingolipid metabolic process
phospholipid biosynthetic process
L-serine transport
positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
positive regulation of serine C-palmitoyltransferase activity
lipid metabolic process
positive regulation of transferase activity
cation transmembrane transport
L-alpha-amino acid transmembrane transport
