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SERPINB3 Antibody (H00006317-D01P) in WB
Western Blot analysis of SERPINB3 expression in transfected 293T cell line (H00006317-T04) by SERPINB3 MaxPab polyclonal antibody.
Lane 1: SERPINB3 transfected lysate(44.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: SERPINB3 transfected lysate(44.60 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00006317-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SERPINB3 (NP_008850.1, 1 a.a. approximately 390 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MNSLSEANTK FMFDLFQQFR KSKENNIFYS PISITSALGM VLLGAKDNTA QQIKKVLHFD QVTENTTGKA ATYHVDRSGN VHHQFQKLLT EFNKSTDAYE LKIANKLFGE KTYLFLQEYL DAIKKFYQTS VESVDFANAP EESRKKINSW VESQTNEKIK NLIPEGNIGS NTTLVLVNAI YFKGQWEKKF NKEDTKEEKF WPNKNTYKSI QMMRQYTSFH FASLEDVQAK VLEIPYKGKD LSMIVLLPNE IDGLQKLEEK LTAEKLMEWT SLQNMRETRV DLHLPRFKVE ESYDLKDTLR TMGMVDIFNG DADLSGMTGS RGLVLSGVLH KAFVEVTEEG AEAAAATAVV GFGSSPTSTN EEFHCNHPFL FFIRQNKTNS ILFYGRFSSP
靶标信息
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein T4-A; SCCA-1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; Serpin B3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; spb3; Squamous cell carcinoma antigen 1
基因别名: HsT1196; SCC; SCCA; SCCA-1; SCCA-PD; SCCA1; SERPINB3; SSCA1; T4-A
UniProt ID: (Human) P29508
Entrez Gene ID: (Human) 6317
positive regulation of cell proliferation
negative regulation of peptidase activity
positive regulation of epithelial to mesenchymal transition
positive regulation of endopeptidase activity
negative regulation of endopeptidase activity
positive regulation of cell migration
autocrine signaling
paracrine signaling
negative regulation of catalytic activity
negative regulation of JUN kinase activity
negative regulation of proteolysis
viral entry into host cell
