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SERPINE2 Antibody (PA5-32163) in IHC (P)
Immunohistochemistry analysis of SERPINE2 was performed on equine endometrial tissue sections. 5-µm-thick sections were prepared from formalin-fixed paraffin-embedded tissue blocks and were dried on slide plate at 37°C overnight. The sections were placed in a Bond Max Automated Immunohistochemistry Vision Biosystem (Leica Microsystems GmbH, Wetzlar, Germany) according to the following protocol. First, tissu... View More
产品信息
PA5-32163
应用
建议稀释比
已发表文章
产品规格
种属反应
Horse,
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 163 and 385 of Human SERPINE2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2549636
产品详细信息
Recommended positive controls: HeLa, HepG2, mouse brain.
Predicted reactivity: Mouse (87%), Rat (87%), Pig (94%), Chicken (82%), Bovine (93%).
PA5-32163 detects SERPINE2 protein in formalin-fixed paraffin-embedded equine endometrial tissue.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GDN; Glia derived nexin; Glia-derived nexin; Glia-derived nexin-like protein; glial-derived neurite promoting factor; P17; Peptidase inhibitor 7; PI-7; PN-1; Protease nexin 1; Protease nexin I; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine protease inhibitor 4; Serine protease-inhibitor 4; Serpin E2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; SERPINE 2
基因别名: B230326M24Rik; GDN; GDNPF; PAI-1; PI-7; PI7; PN-1; PN1; PNI; SERPINE2; Spi4
UniProt ID: (Human) Q5D0C4, (Mouse) Q07235
Entrez Gene ID: (Human) 5270, (Horse) 100056744, (Mouse) 20720
embryo implantation
blood coagulation
negative regulation of cell proliferation
response to radiation
negative regulation of plasminogen activation
negative regulation of sodium ion transport
negative regulation of endopeptidase activity
negative regulation of protein processing
positive regulation of neuron projection development
negative regulation of phosphatidylinositol 3-kinase signaling
cerebellar granular layer morphogenesis
negative regulation of blood coagulation
negative regulation of cell growth
regulation of cell migration
secretion by cell
secretory granule organization
negative regulation of protein catabolic process
mating plug formation
negative regulation of proteolysis
negative regulation of smoothened signaling pathway
regulation of timing of cell differentiation
positive regulation of astrocyte differentiation
detection of mechanical stimulus involved in sensory perception
regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
innervation
seminal vesicle epithelium development
dense core granule biogenesis
negative regulation of platelet aggregation
multicellular organism development
nervous system development
response to wounding
negative regulation of peptidase activity
negative regulation of platelet activation
cell differentiation
