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SERPINF2 Antibody (PA5-87074) in IHC (P)
Immunohistochemistry analysis of SERPINF2 in paraffin-embedded rat pancreas. Samples were incubated with SERPINF2 polyclonal antibody (Product # PA5-87074) using a dilution of 1:100. Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-87074
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein of human SERPINF2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2803827
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 2 antiplasmin; Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; pigment epithelium derived factor; plasmin inhibitor alpha 2; serine (or cysteine) peptidase inhibitor, clade F, member 2; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2; serine (or cysteine) proteinase inhibitor, clade F, member 2; Serpin F2; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
基因别名: A2AP; AAP; AI747498; ALPHA-2-PI; API; PLI; Serpimf2; SERPINF2
UniProt ID: (Human) P08697, (Mouse) Q61247
Entrez Gene ID: (Human) 5345, (Mouse) 18816, (Rat) 287527
regulation of blood vessel size by renin-angiotensin
platelet degranulation
acute-phase response
response to organic substance
negative regulation of plasminogen activation
negative regulation of endopeptidase activity
collagen fibril organization
positive regulation of collagen biosynthetic process
fibrinolysis
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
blood vessel morphogenesis
positive regulation of smooth muscle cell proliferation
positive regulation of stress fiber assembly
negative regulation of fibrinolysis
positive regulation of ERK1 and ERK2 cascade
positive regulation of transforming growth factor beta production
positive regulation of cell-cell adhesion mediated by cadherin
negative regulation of peptidase activity
