Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
MA5-29798
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
128
抗原
Recombinant Mouse SerpinF2 protein (Met1-Lys491)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2785620
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse Serpin F2/SERPINF2.
靶标信息
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: alpha 2 antiplasmin; Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; pigment epithelium derived factor; plasmin inhibitor alpha 2; serine (or cysteine) proteinase inhibitor, clade F, member 2; Serpin F2
基因别名: AI747498; Pli; Serpimf2; Serpinf2
UniProt ID: (Mouse) Q61247
Entrez Gene ID: (Mouse) 18816
regulation of blood vessel size by renin-angiotensin
acute-phase response
negative regulation of peptidase activity
negative regulation of plasminogen activation
negative regulation of endopeptidase activity
collagen fibril organization
positive regulation of collagen biosynthetic process
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
blood vessel morphogenesis
positive regulation of smooth muscle cell proliferation
positive regulation of stress fiber assembly
negative regulation of fibrinolysis
positive regulation of ERK1 and ERK2 cascade
positive regulation of transforming growth factor beta production
