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SERPINF2 Antibody (MA5-51011) in IHC (P)
Immunohistochemistry (Paraffin) analysis of SERPINF2 in Human Kidney Tissue. Samples were incubated in SERPINF2 monoclonal antibody (Product # MA5-51011) using a dilution of 20 µg/mL followed by HRP-Linked Caprine Anti-Mouse IgG at a dilution of 2 µg/mL and DAB staining.
产品信息
MA5-51011
产品规格
种属反应
Human,
Pig
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
C3
抗原
Recombinant Human a2PI protein (Accession #P08697)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% Proclin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3090598
靶标信息
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2; Serpin F2; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
基因别名: A2AP; AAP; ALPHA-2-PI; API; PLI; SERPINF2
UniProt ID: (Human) P08697
Entrez Gene ID: (Pig) 100525254, (Human) 5345
regulation of blood vessel size by renin-angiotensin
platelet degranulation
acute-phase response
response to organic substance
negative regulation of plasminogen activation
negative regulation of endopeptidase activity
collagen fibril organization
positive regulation of collagen biosynthetic process
fibrinolysis
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
blood vessel morphogenesis
positive regulation of smooth muscle cell proliferation
positive regulation of stress fiber assembly
negative regulation of fibrinolysis
positive regulation of ERK1 and ERK2 cascade
positive regulation of transforming growth factor beta production
positive regulation of cell-cell adhesion mediated by cadherin
