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产品信息
PA5-100329
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SESN3(Accession P58005), corresponding to amino acid residues H311-F361.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2849843
产品详细信息
Antibody detects endogenous levels of total SESN3.
靶标信息
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Sestrin-3
基因别名: 5630400E15Rik; BC003348; SESN3; SEST3
UniProt ID: (Human) P58005, (Mouse) Q9CYP7
Entrez Gene ID: (Human) 143686, (Rat) 315427, (Mouse) 75747
