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SESN3 Antibody (PA5-22220) in WB
SESN3 Polyclonal Antibody detects SESN3 protein by western blot analysis. A. 30 µg Rat2 whole cell lysate/extract.7.5% SDS-PAGE. SESN3 Polyclonal Antibody (Product # PA5-22220) dilution: 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
PA5-22220
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 21 and 296 of SESN3 (Uniprot ID#P58005)
偶联物
形式
Liquid
浓度
1.36 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11155598
产品详细信息
Recommended positive controls: HeLa, Raw264.7, C2C12, Rat2.
Predicted reactivity: Mouse (94%), Rat (93%), Xenopus laevis (80%), Rhesus Monkey (98%), Chimpanzee (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Sestrin-3
基因别名: 5630400E15Rik; BC003348; SESN3; SEST3
UniProt ID: (Human) P58005, (Mouse) Q9CYP7
Entrez Gene ID: (Human) 143686, (Rat) 315427, (Mouse) 75747
