Invitrogen

SETD3 Polyclonal Antibody

抗体检测数据 (4)

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SETD3 Antibody (PA5-82111) in IHC (P)

Immunohistochemical analysis of SETD3 in human testis using SETD3 Polyclonal Antibody (Product # PA5-82111) shows moderate cytoplasmic positivity in cells in seminiferous ducts.

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SETD3 in human testis using SETD3 Polyclonal Antibody (Product # PA5-82111) shows moderate cytoplasmic positivity in cells in seminiferous ducts.

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SETD3 in human placenta using SETD3 Polyclonal Antibody (Product # PA5-82111) shows moderate cytoplasmic positivity in trophoblastic cells.

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SETD3 in human kidney using SETD3 Polyclonal Antibody (Product # PA5-82111) shows moderate cytoplasmic positivity in cells in tubules.

SETD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SETD3 in human liver using SETD3 Polyclonal Antibody (Product # PA5-82111) shows no expression in hepatocytes as expected.

产品信息

PA5-82111

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

-

免疫组化（石蜡） (IHC (P))

1:50-1:200

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human SETD3. Recombinant protein control fragment (Product #RP-89072).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2789272

产品详细信息

Immunogen sequence: SGTGATATVS PKEILNLTSE LLQKCSSPAP GPGKEWEEYV QIRTLVEKIR KKQKGLSVTF DGKREDYFPD LMKWASENGA SVEGFEMVNF KEEGFGLRAT RDIKAEELFL WVPRKLLMTV E

靶标信息

SETD3 is a histone methyltransferase that is involved in epigenetic transcriptional activation by methylating lysine residues on histone H3 tails.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Actin-histidine N-methyltransferase; hSETD3; Protein-L-histidine N-tele-methyltransferase; SET domain-containing protein 3

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基因别名: C14orf154; SETD3

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UniProt ID: (Human) Q86TU7

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Entrez Gene ID: (Human) 84193

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RNA polymerase II activating transcription factor binding transcription coactivator activity histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K4 specific) histone methyltransferase activity (H3-K36 specific) methyltransferase

参与通路

transcription, DNA-templated histone H3-K36 methylation peptidyl-lysine trimethylation peptidyl-lysine monomethylation peptidyl-lysine dimethylation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of muscle cell differentiation histone H3-K4 methylation