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Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human A549 whole cell, human U2OS whole cell, human PC-3 whole cell, rat heart tissue, mouse heart tissue, mouse HEPA1-6 whole cell. IHC: human colon cancer tissue, human lung cancer tissue, mouse intestine tissue, mouse kidney tissue, rat kidney tissue, rat intestine tissue. ICC/IF: U20S cell. Flow: A549 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: frizzled-related protein; FRP-1; SARP-2; Secreted apoptosis-related protein 2; Secreted frizzled-related protein 1; secreted frizzled-related sequence protein 1; sFRP-1
Gene Aliases: 2210415K03Rik; AW011917; AW107218; AW742929; FRP; FRP-1; FRP1; FrzA; SARP2; sFRP-1; SFRP1
UniProt ID: (Human) Q8N474, (Mouse) Q8C4U3
Entrez Gene ID: (Human) 6422, (Mouse) 20377, (Rat) 84402
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