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SFRP5 Antibody (PA5-71770) in IHC (P)
Immunohistochemistry analysis of SFRP5 in paraffin-embedded Human pancreas tissue. Samples were incubated with SFRP5 polyclonal antibody (Product # PA5-71770) using a dilution of 1:500 for 1 hour at room temperature followed by an undiluted biotinylated CRF Anti-Polyvalent HRP Polymer antibody.
Product Details
PA5-71770
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of human SFRP5
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2717624
Target Information
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Frizzled-related protein 1b; FRP-1b; SARP-3; secreted apoptosis related protein 3; Secreted apoptosis-related protein 3; Secreted frizzled-related protein 5; sFRP-5
Gene Aliases: AI605071; FRP1B; SARP3; SFRP5
UniProt ID: (Human) Q5T4F7, (Mouse) Q9WU66
Entrez Gene ID: (Human) 6425, (Mouse) 54612
apoptotic process
establishment or maintenance of cell polarity
signal transduction
G-protein coupled receptor signaling pathway
multicellular organism development
visual perception
negative regulation of cell proliferation
anatomical structure morphogenesis
cell differentiation
negative regulation of Wnt signaling pathway
negative regulation of catenin import into nucleus
non-canonical Wnt signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of protein kinase B signaling
negative regulation of canonical Wnt signaling pathway
negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis
Wnt signaling pathway
post-anal tail morphogenesis
negative regulation of JUN kinase activity
digestive tract morphogenesis
convergent extension involved in axis elongation
canonical Wnt signaling pathway
regulation of establishment of planar polarity
planar cell polarity pathway involved in neural tube closure
negative regulation of planar cell polarity pathway involved in axis elongation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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