Search Thermo Fisher Scientific
This antibody detects endogenous protein at a molecular weight of 105 kDa.
Purity is >95% by SDS-PAGE.
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: serine/arginine-rich splicing factor 8; Splicing factor, arginine/serine-rich 8; splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila); splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot, Drosophila homolog); splicing factor, suppressor of white-apricot family; Splicing factor, suppressor of white-apricot homolog; Suppressor of white apricot protein homolog
基因别名: 1190005N23Rik; 6330437E22Rik; AI197402; AW212079; SFRS8; SFSWAP; Srsf8; SWAP
UniProt ID: (Human) Q12872, (Mouse) Q3USH5, (Rat) D3ZTQ1
Entrez Gene ID: (Human) 6433, (Mouse) 231769, (Rat) 304431