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产品信息
PA5-79987
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1/2 (206-237aa VNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRN).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2747102
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-D and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 45 ng/mL in healthy individuals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein; collectin 5; Collectin-4; Collectin-5; FLJ50593; FLJ51913; FLJ61144; FLJ77898; FLJ79095; FLJ99559; MGC133365; MGC198590; PSAP; PSP-A; Pulmonary surfactant-associated protein A; Pulmonary surfactant-associated protein A1; Pulmonary surfactant-associated protein A2; SP-2A beta; SP-2A gamma; SP-A1 beta; SP-A1 delta; SP-A1 epsilon; SP-A1 gamma; SP-A2; SP-A2 alpha; SP-A2 delta; surfactant associated protein A; surfactant protein A1 variant AB'D' 6A; surfactant protein A1 variant AB'D' 6A2; surfactant protein A1 variant AB'D' 6A3; surfactant protein A1 variant AB'D' 6A4; surfactant protein A1 variant ACD' 6A; surfactant protein A1 variant ACD' 6A2; surfactant protein A1 variant ACD' 6A3; surfactant protein A1 variant ACD' 6A4; surfactant protein A1 variant AD' 6A; surfactant protein A1 variant AD' 6A2; surfactant protein A1 variant AD' 6A3; surfactant protein A1 variant AD' 6A4; surfactant protein A1B; surfactant pulmonary associated protein A1; surfactant, pulmonary-associated protein A1; surfactant, pulmonary-associated protein A1A; surfactant, pulmonary-associated protein A1B; surfactant, pulmonary-associated protein A2A; Surfactant-associated protein 1 (pulmonary surfactant protein SP-A); Surfactant-associated protein 1 (pulmonary surfactant protein, SP-A)
基因别名: COLEC4; COLEC5; PSAP; PSP-A; PSPA; Sftp-1; SFTP1; SFTPA; SFTPA1; SFTPA1B; SFTPA2; SFTPA2B; Sftpl; SP-2A; SP-A; SP-A1; SPA; SPA1; SPA2; SPAII
UniProt ID: (Human) Q8IWL2, (Human) Q8IWL1, (Rat) P08427
Entrez Gene ID: (Human) 653509, (Human) 729238, (Rat) 24773, (Mouse) 20387
lipid transport
respiratory gaseous exchange
cellular protein metabolic process
response to hypoxia
circadian rhythm
response to hormone
response to lipopolysaccharide
response to retinoic acid
response to vitamin A
positive regulation of phagocytosis
response to glucocorticoid
response to hyperoxia
response to interleukin-6
response to epidermal growth factor
cellular response to mechanical stimulus
cellular response to nitric oxide
