Invitrogen

SGK1 Polyclonal Antibody

图: 1 / 3

SGK1 Antibody (PA5-85237) in WB

Western Blot analysis of SGK1 was performed by separating 30 µg of non-transfected (–) and transfected (+) 293T whole cell extracts by 10% SDS-PAGE. Proteins were transferred to a membrane and probed with a SGK1 Polyclonal Antibody (Product # PA5-85237) at a dilution of 1:5000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody., and the signal was developed with Trident ECL plus-Enhanced

Product Image Gallery

产品信息

PA5-85237

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:10,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein encompassing a sequence within the center region of human SGK1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.38 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2792380

产品详细信息

Keep as concentrated solution.

Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (88%), Xenopus laevis (91%), Pig (95%), Rabbit (95%), Chicken (94%), Chimpanzee (100%), Bovine (95%).

Positive Control: mouse brain.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: serine/threonine protein kinase SGK; Serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; Serum/glucocorticoid-regulated kinase 1; Sgk1 variant i3

查看更多收起

基因别名: SGK; SGK1

查看更多收起

UniProt ID: (Human) O00141, (Mouse) Q9WVC6

查看更多收起

Entrez Gene ID: (Human) 6446, (Mouse) 20393

查看更多收起

功能