Invitrogen

SGSH Polyclonal Antibody

SGSH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SGSH Antibody (PA5-82831) in IHC (P)

Immunohistochemical analysis of SGSH in human adrenal gland using SGSH Polyclonal Antibody (Product # PA5-82831) shows strong cytoplasmic granular positivity in glandular cells.

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SGSH Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of SGSH demonstrates antibody specificity. Immunohistochemical analysis of SGSH using anti-SGSH Polyclonal Antibody (Product #PA5-82831), shows significant staining of SGSH in adrenal gland and shows minimal or weak staining in skeletal muscle tissues. The relative expression levels of SGSH within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-82831

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human SGSH. Recombinant protein control fragment (Product #RP-93497).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2789987

产品详细信息

Immunogen sequence: CEKFGNGESG MGRIPDWTPQ AYDPLDVLVP YFVPNTPAAR ADLAAQYTTV GRMDQGVGLV LQELRDAGVL NDTLVIFTSD NGIPFPSGRT NLYWPGTAEP L

靶标信息

SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。