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SH2D1B Antibody (PA5-106376) in IHC (P)
Immunohistochemistry analysis of SH2D1B in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SH2D1B polyclonal antibody (Product # PA5-106376) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-106376
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SH2D1B(Accession O14796), corresponding to amino acid residues K85-P132.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854051
产品详细信息
Antibody detects endogenous levels of total SH2D1B.
靶标信息
SH2D1B plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EAT-2; EWS/FLI1 activated transcript 2; EWS/FLI1-activated transcript 2; SH2 domain containing 1B; SH2 domain protein 1B1; SH2 domain-containing molecule EAT2; SH2 domain-containing protein 1B
基因别名: EAT-2; EAT-2A; EAT2; Eat2a; RGD1563935; SH2D1B; Sh2d1b1
UniProt ID: (Human) O14796
Entrez Gene ID: (Human) 117157, (Rat) 501869, (Mouse) 26904
adaptive immune response
leukocyte activation involved in immune response
positive regulation of natural killer cell mediated immunity
innate immune response
positive regulation of innate immune response
regulation of immune response
natural killer cell inhibitory signaling pathway
positive regulation of signal transduction
peptidyl-tyrosine phosphorylation
negative regulation of interferon-gamma production
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of peptidyl-tyrosine phosphorylation
biological_process
